Across TCGA pan-cancer cohorts, DMRTC1B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated DMRTC1B data layer.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DMRTC1B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DMRTC1B expression acts as an unfavorable survival marker, although some lineages such as ESCA and KIRP show a favorable association.
UCEC, ESCA, and KIRP are the cancer types where DMRTC1B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.