DMRTA2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DMRTA2 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible DMRTA2-associated genes across cancer lineages are Fibroblasts. Each is linked with DMRTA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMRTA2-to-partner and partner-to-DMRTA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by DMRTA2-low versus DMRTA2-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTA2→partner) and Y-score (partner→DMRTA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SCLCFibroblasts →+0.032+4.643<.001.00332
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Fibroblasts by DMRTA2 expression — SCLC

Box plot of Fibroblasts in DMRTA2-low vs DMRTA2-high samples in SCLC.

Explore this box plot interactively →

Exploration