DMRTA2

Across TCGA cell cohorts, DMRTA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,706 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DMRTA2-associated GO terms across cancer lineages are Regulation of ubiquitin protein ligase activity, Nucleic acid transport, and RNA transport. Each is linked with DMRTA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both DMRTA2-to-partner and partner-to-DMRTA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ubiquitin protein ligase activity grouped by DMRTA2-low versus DMRTA2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTA2→partner) and Y-score (partner→DMRTA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of ubiquitin protein ligase activity →	+0.168	+0.190	.003	<.001	3	5
OESOPHAGUS	Nucleic acid transport →	+0.095	+1.493	.006	.004	3	5
OESOPHAGUS	RNA transport →	+0.095	+1.493	.006	.004	3	5
CNS	DNA geometric change →	+0.073	+1.293	<.001	.001	3	5
BREAST	Negative regulation of cell cycle process →	+0.059	+0.312	<.001	.006	3	5
BREAST	Mitotic chromosome condensation →	+0.177	+0.609	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,706 associations by consensus.

Regulation of ubiquitin protein ligase activity by DMRTA2 expression — BONE

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