DMRTA1

Across TCGA cell cohorts, DMRTA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,037 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DMRTA1-associated GO terms across cancer lineages are Indole-containing compound metabolic process, Mitochondrial depolarization, and Cellular response to growth hormone stimulus. Each is linked with DMRTA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DMRTA1-to-partner and partner-to-DMRTA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Indole-containing compound metabolic process grouped by DMRTA1-low versus DMRTA1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRTA1→partner) and Y-score (partner→DMRTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Indole-containing compound metabolic process →	-0.171	-0.653	<.001	<.001	3	7
LARGE_INTESTINE	Mitochondrial depolarization →	+0.086	+0.132	.001	.001	3	6
LUNG_NSCLC_LUAD	Cellular response to growth hormone stimulus →	-0.076	-0.507	<.001	<.001	3	5
SOFT_TISSUE	Positive regulation of organ growth →	-0.128	-0.520	<.001	.004	3	5
OVARY	Positive regulation of heart growth →	-0.117	-0.584	<.001	<.001	3	5
SOFT_TISSUE	Response to unfolded protein →	+0.050	+0.361	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,037 associations by consensus.

Indole-containing compound metabolic process by DMRTA1 expression — BONE

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