DMRT3

Across TCGA patient cohorts, DMRT3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,636 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DMRT3-associated proteins across cancer lineages are THYN1, CARM1, and ARHGEF26_S392. Each is linked with DMRT3 in more than 3 cancer types. Because this analysis shows association rather than direction, both DMRT3-to-partner and partner-to-DMRT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMRT3 versus THYN1 in LUAD, with a Pearson correlation of -0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRT3→partner) and Y-score (partner→DMRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	THYN1 →	-0.269	-0.214	<.001	.004	3	4
CCRCC	CARM1 →	+0.196	+0.146	<.001	<.001	3	4
HNSC	ARHGEF26_S392 →	+1.668	+1.549	<.001	.001	3	3
LSCC	RAB6B →	+0.996	+0.836	<.001	<.001	3	3
HNSC	RABGGTB →	-0.203	-0.625	<.001	.003	3	3
OV	ZBTB33 →	+0.294	+0.368	.005	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,636 associations by consensus.

DMRT3 vs THYN1 — LUAD

Explore this scatter interactively →