DMRT3

Across TCGA cell cohorts, DMRT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,036 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DMRT3-associated GO terms across cancer lineages are Cellular respiration, Regulation of ferroptosis, and DNA replication-dependent chromatin assembly. Each is linked with DMRT3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DMRT3-to-partner and partner-to-DMRT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular respiration grouped by DMRT3-low versus DMRT3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRT3→partner) and Y-score (partner→DMRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Cellular respiration →	+0.048	+0.151	<.001	.006	3	6
OVARY	Regulation of ferroptosis →	+0.095	+0.515	<.001	.004	3	5
UPPER_AERODIGESTIVE_TRACT	DNA replication-dependent chromatin assembly →	+0.125	+0.446	<.001	.004	3	5
UPPER_AERODIGESTIVE_TRACT	Mitochondrial membrane organization →	+0.085	+0.184	<.001	.007	3	5
BLOOD_Lymphoma	Energy derivation by oxidation of organic compounds →	+0.044	+0.155	<.001	.005	3	5
OESOPHAGUS	Chemical synaptic transmission, postsynaptic →	-0.065	-0.634	.005	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,036 associations by consensus.

Cellular respiration by DMRT3 expression — BLOOD_Lymphoma

Explore this box plot interactively →