DMRT1

Across TCGA patient cohorts, DMRT1 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,449 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DMRT1-associated proteins across cancer lineages are CAND1, AKNA_S537, and RPS6KC1_S528. Each is linked with DMRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMRT1-to-partner and partner-to-DMRT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMRT1 versus CAND1 in UCEC, with a Pearson correlation of 0.97.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMRT1→partner) and Y-score (partner→DMRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CAND1 →	+0.486	+2.778	.005	.007	2	1
UCEC	AKNA_S537 →	-0.466	-0.843	.005	.008	2	1
UCEC	RPS6KC1_S528 →	-0.293	-0.866	.009	.005	2	1
UCEC	SH3BP4_S296 →	-0.439	-0.843	.001	.008	2	1
UCEC	TINF2 →	-0.300	-0.726	.007	.005	2	1
UCEC	VMA21 →	+2.299	+0.843	.005	.008	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,449 associations by consensus.

DMRT1 vs CAND1 — UCEC

Explore this scatter interactively →