DMPK

Across TCGA patient cohorts, DMPK RNA expression is significantly associated with the protein abundance of many other proteins, with 13,480 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DMPK-associated proteins across cancer lineages are VCAN, SGCD, and TGFBI. Each is linked with DMPK in more than 5 cancer types. Because this analysis shows association rather than direction, both DMPK-to-partner and partner-to-DMPK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMPK versus VCAN in CCRCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMPK→partner) and Y-score (partner→DMPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	VCAN →	+1.006	+0.402	<.001	<.001	3	6
HNSC	SGCD →	+0.764	+0.624	<.001	<.001	3	6
CCRCC	TGFBI →	+0.774	+0.519	<.001	<.001	3	5
COAD	SORBS1 →	+0.759	+0.578	<.001	.004	3	5
PDAC	C2 →	+0.592	+0.294	<.001	.002	3	5
COAD	FERMT2 →	+0.653	+0.659	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,480 associations by consensus.

DMPK vs VCAN — CCRCC

Explore this scatter interactively →