DMPK

Across TCGA patient cohorts, DMPK protein abundance is significantly associated with the RNA expression of many other genes, with 4,621 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DMPK-associated genes across cancer lineages are SGCA, PMP22, and CNRIP1. Each is linked with DMPK in more than 4 cancer types. Because this analysis shows association rather than direction, both DMPK-to-partner and partner-to-DMPK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMPK versus SGCA in HNSC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMPK→partner) and Y-score (partner→DMPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SGCA →	+2.397	+1.066	<.001	<.001	3	5
HNSC	PMP22 →	+1.063	+1.040	<.001	.001	3	5
UCEC	CNRIP1 →	+0.982	+0.923	<.001	<.001	3	5
HNSC	F13A1 →	+1.823	+0.762	<.001	<.001	3	5
UCEC	RHOJ →	+0.879	+0.661	<.001	.002	3	5
COAD	DDR2 →	+0.850	+0.571	.006	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,621 associations by consensus.

DMPK vs SGCA — HNSC

Explore this scatter interactively →