DMPK

Across TCGA cell cohorts, DMPK RNA expression is significantly associated with the go_rna of many other GO terms, with 5,382 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DMPK-associated GO terms across cancer lineages are Cytosolic transport, Regulation of organelle assembly, and Regulation of cilium assembly. Each is linked with DMPK in more than 16 cancer types. Because this analysis shows association rather than direction, both DMPK-to-partner and partner-to-DMPK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by DMPK-low versus DMPK-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMPK→partner) and Y-score (partner→DMPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cytosolic transport →	+0.076	+1.088	<.001	.001	3	17
URINARY_TRACT	Regulation of organelle assembly →	+0.043	+1.137	<.001	.001	3	16
BREAST	Regulation of cilium assembly →	+0.065	+1.200	.001	<.001	2	17
OESOPHAGUS	mRNA splice site recognition →	+0.145	+1.339	.001	<.001	3	15
BREAST	Retrograde transport, endosome to Golgi →	+0.070	+1.221	<.001	<.001	3	15
STOMACH	Endosomal transport →	+0.078	+1.691	.002	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,382 associations by consensus.

Cytosolic transport by DMPK expression — SKIN

Explore this box plot interactively →