DMKN

Across TCGA patient cohorts, DMKN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,325 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DMKN-associated proteins across cancer lineages are EVPL, PPP1R13L, and NAA35. Each is linked with DMKN in more than 4 cancer types. Because this analysis shows association rather than direction, both DMKN-to-partner and partner-to-DMKN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMKN versus EVPL in HNSC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMKN→partner) and Y-score (partner→DMKN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EVPL →	+0.685	+1.412	<.001	<.001	3	5
HNSC	PPP1R13L →	+0.525	+1.304	<.001	<.001	3	4
HNSC	NAA35 →	+0.242	+1.445	<.001	<.001	3	4
COAD	S100A2 →	+1.732	+1.691	<.001	<.001	3	4
HNSC	SFN →	+1.026	+1.457	<.001	<.001	3	4
LSCC	CEP170B →	+0.352	+1.246	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,325 associations by consensus.

DMKN vs EVPL — HNSC

Explore this scatter interactively →