Across TCGA patient cohorts, DMBX1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DMBX1-associated genes across cancer lineages are FASN, EGFR_pY1068, and p62 Lck ligand. Each is linked with DMBX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMBX1-to-partner and partner-to-DMBX1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMBX1→partner) and Y-score (partner→DMBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.383	+2.000	.031	.032	3	2
UCEC	EGFR_pY1068 →	-0.281	-2.000	.013	.032	3	1
UCEC	p62 Lck ligand →	+0.453	+2.700	.001	.006	3	1
UCEC	PCNA →	+0.195	+2.999	.045	.035	3	1
UCEC	Rab25 →	-0.454	-2.000	.002	.032	3	1
UCEC	Tuberin →	+0.340	+2.000	.005	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

DMBX1 survival (RNA) · tumor vs normal (RNA) · all DMBX1 data types