Across TCGA cell cohorts, DMBX1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DMBX1-associated genes across cancer lineages are DCD, RBMY1E, and POM121L12. Each is linked with DMBX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMBX1-to-partner and partner-to-DMBX1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMBX1→partner) and Y-score (partner→DMBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DCD →	+0.046	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	RBMY1E →	+0.820	+4.643	.002	.008	3	1
LUNG_NSCLC_LUAD	POM121L12 →	+0.022	+5.266	<.001	.001	3	1
SKIN	GGTLC2 →	+0.029	+4.273	.001	.006	3	1
SKIN	CRYGD →	+0.530	+4.415	<.001	.007	3	1
SKIN	TMEM235 →	+0.006	+5.217	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

DMBX1 survival (RNA) · tumor vs normal (RNA) · all DMBX1 data types