Across TCGA pan-cancer cohorts, DMBT1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DMBT1 data layer compared with 27 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher DMBT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DMBT1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

UCEC, PDAC, and LUAD are the cancer types where DMBT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	0.424	1.000	.003	20	view →
PDAC	OS	Median	IV	0.395	0.937	.026	5	view →
LUAD	DFS	Quartile	All	0.829	0.994	.022	4	view →
LSCC	DFS	Median	III,IV	1.000	0.867	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: DMBT1 tumor-vs-normal RNA expression · all DMBT1 data types