Across TCGA patient cohorts, DMBT1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,444 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DMBT1-associated genes across cancer lineages are DHX35, LRG1, and TMC5. Each is linked with DMBT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DMBT1-to-partner and partner-to-DMBT1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMBT1→partner) and Y-score (partner→DMBT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX35 →	-0.649	-0.807	<.001	.002	3	4
OV	LRG1 →	+1.875	+1.300	.003	.004	2	5
LSCC	TMC5 →	+1.615	+0.865	<.001	.001	3	4
LUAD	ERN2 →	+1.696	+0.927	<.001	<.001	3	4
LUAD	SELENBP1 →	+1.417	+1.298	<.001	<.001	3	4
LSCC	SLC44A4 →	+1.806	+1.163	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,444 associations by consensus.

Exploration

DMBT1 survival (RNA) · tumor vs normal (RNA) · all DMBT1 data types