Across TCGA patient cohorts, DMBT1 mutation is significantly associated with the RNA expression of many other genes, with 5,538 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible DMBT1-associated genes across cancer lineages are CDCA2, BCCIP, and MRPS15. Each is linked with DMBT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DMBT1-to-partner and partner-to-DMBT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMBT1→partner) and Y-score (partner→DMBT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDCA2 →	+0.572	+1.760	.004	.004	3	5
SKCM	BCCIP →	+0.358	+1.438	<.001	<.001	3	5
LUAD	MRPS15 →	+0.347	+3.854	.003	<.001	3	5
LUAD	PIMREG →	+0.769	+2.471	<.001	<.001	3	5
SKCM	BUB3 →	+0.283	+1.624	<.001	<.001	3	5
LUAD	SKA1 →	+0.749	+2.105	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,538 associations by consensus.

Exploration

DMBT1 survival (RNA) · tumor vs normal (RNA) · all DMBT1 data types