Across TCGA cell cohorts, DMBT1 mutation is significantly associated with the RNA expression of many other genes, with 1,785 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DMBT1-associated genes across cancer lineages are SLC25A19, SLC18B1, and MRGPRX1. Each is linked with DMBT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DMBT1-to-partner and partner-to-DMBT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMBT1→partner) and Y-score (partner→DMBT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC25A19 →	+0.495	+3.252	.002	.002	3	3
LARGE_INTESTINE	SLC18B1 →	+0.778	+3.584	<.001	<.001	3	3
URINARY_TRACT	MRGPRX1 →	+0.157	+4.087	.001	.009	3	2
LARGE_INTESTINE	C9orf153 →	+0.114	+1.768	.001	.005	3	2
SOFT_TISSUE	HMHB1 →	+0.378	+3.635	<.001	.007	3	2
SOFT_TISSUE	C10orf120 →	+0.018	+4.392	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,785 associations by consensus.

Exploration

DMBT1 survival (RNA) · tumor vs normal (RNA) · all DMBT1 data types