DMAP1

Across TCGA pan-cancer cohorts, DMAP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DMAP1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher DMAP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DMAP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, CCRCC, and LUAD are the cancer types where DMAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.919	0.655	.007	22	view →
CCRCC	DFS	Tertile	All	1.000	0.559	.001	11	view →
LUAD	OS	Median	III,IV	0.683	0.212	.008	11	view →
PDAC	DFS	Median	IV	0.785	0.214	.006	10	view →
GBM	DFS	Quartile	All	0.362	0.221	.017	8	view →
HNSC	DFS	Median	All	0.704	0.839	.025	7	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DMAP1–LSCC (OS)

Open the LSCC breakdown →