DMAP1

Across TCGA patient cohorts, DMAP1 mutation is significantly associated with the RNA expression of many other genes, with 1,522 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DMAP1-associated genes across cancer lineages are HIRA, RHBDD3, and DHRS2. Each is linked with DMAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DMAP1-to-partner and partner-to-DMAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIRA grouped by DMAP1-low versus DMAP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DMAP1→partner) and Y-score (partner→DMAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HIRA →	+0.448	+3.354	.003	.005	3	2
UCEC	RHBDD3 →	+0.477	+3.617	.002	.001	3	2
UCEC	DHRS2 →	+1.606	+3.470	<.001	.002	3	2
UCEC	RBFA →	+0.477	+3.467	<.001	.002	3	2
UCEC	NAGPA →	+0.444	+3.595	<.001	.001	3	2
UCEC	TIMM44 →	+0.451	+4.202	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,522 associations by consensus.

HIRA by DMAP1 expression — UCEC

Explore this box plot interactively →