DMAP1

Across TCGA cell cohorts, DMAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,390 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DMAP1-associated GO terms across cancer lineages are Regulation of transcription initiation by RNA polymerase II, RNA catabolic process, and Nucleic acid catabolic process. Each is linked with DMAP1 in more than 15 cancer types. Because this analysis shows association rather than direction, both DMAP1-to-partner and partner-to-DMAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription initiation by RNA polymerase II grouped by DMAP1-low versus DMAP1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMAP1→partner) and Y-score (partner→DMAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of transcription initiation by RNA polymerase II →	+0.066	+0.676	<.001	<.001	3	16
BONE	RNA catabolic process →	+0.082	+0.736	<.001	.002	3	16
BONE	Nucleic acid catabolic process →	+0.072	+0.752	<.001	.006	3	16
BONE	Regulation of RNA splicing →	+0.079	+0.820	.008	.003	3	16
BONE	RISC complex assembly →	+0.155	+1.019	<.001	<.001	3	15
SOFT_TISSUE	Mitotic cell cycle checkpoint signaling →	+0.091	+0.821	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,390 associations by consensus.

Regulation of transcription initiation by RNA polymerase II by DMAP1 expression — PANCREAS

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