DMAC2L

Across TCGA cell cohorts, DMAC2L RNA expression is significantly associated with the go_rna of many other GO terms, with 2,800 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DMAC2L-associated GO terms across cancer lineages are Protein linear polyubiquitination, Double-strand break repair, and Microtubule polymerization. Each is linked with DMAC2L in more than 8 cancer types. Because this analysis shows association rather than direction, both DMAC2L-to-partner and partner-to-DMAC2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by DMAC2L-low versus DMAC2L-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMAC2L→partner) and Y-score (partner→DMAC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein linear polyubiquitination →	+0.130	+0.581	.001	.002	3	9
BREAST	Double-strand break repair →	+0.052	+0.713	.001	<.001	3	9
SOFT_TISSUE	Microtubule polymerization →	+0.079	+0.478	.001	.002	3	9
BLOOD_Myeloma	Negative regulation of TOR signaling →	+0.063	+0.813	.001	.002	3	8
SKIN	Viral RNA genome replication →	+0.075	+0.348	<.001	.002	3	8
SKIN	Positive regulation of mRNA metabolic process →	+0.040	+0.427	.002	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,800 associations by consensus.

Protein linear polyubiquitination by DMAC2L expression — SOFT_TISSUE

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