DMAC2

Across TCGA patient cohorts, DMAC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,128 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DMAC2-associated proteins across cancer lineages are PPP5C, HNRNPUL1, and IRF2BP1. Each is linked with DMAC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both DMAC2-to-partner and partner-to-DMAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMAC2 versus PPP5C in GBM, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMAC2→partner) and Y-score (partner→DMAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP5C →	+0.294	+0.354	<.001	<.001	3	7
OV	HNRNPUL1 →	+0.342	+0.507	.004	<.001	3	6
GBM	IRF2BP1 →	+0.337	+0.296	<.001	<.001	3	6
BRCA	XRCC1 →	+0.415	+0.460	<.001	<.001	3	6
GBM	SAE1 →	+0.407	+0.356	<.001	<.001	3	5
LUAD	TIMM50 →	+0.459	+0.381	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,128 associations by consensus.

DMAC2 vs PPP5C — GBM

Explore this scatter interactively →