DMAC2

Across TCGA cell cohorts, DMAC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,994 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DMAC2-associated GO terms across cancer lineages are Nucleosome disassembly, DNA strand elongation involved in DNA replication, and Meiotic chromosome condensation. Each is linked with DMAC2 in more than 12 cancer types. Because this analysis shows association rather than direction, both DMAC2-to-partner and partner-to-DMAC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleosome disassembly grouped by DMAC2-low versus DMAC2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMAC2→partner) and Y-score (partner→DMAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Nucleosome disassembly →	+0.165	+0.820	.007	.002	3	13
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.116	+0.481	<.001	<.001	3	12
URINARY_TRACT	Meiotic chromosome condensation →	+0.150	+0.685	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair via homologous recombination →	+0.067	+0.683	.007	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of chromatin organization →	+0.093	+0.835	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cytokinesis →	+0.212	+1.022	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,994 associations by consensus.

Nucleosome disassembly by DMAC2 expression — LIVER

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