DMAC1P1

Across TCGA pan-cancer cohorts, DMAC1P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of DMAC1P1’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where DMAC1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types DMAC1P1 is over-expressed in tumor, although a few such as ESCA and LUAD show the opposite, repressed pattern.

ESCA, KICH, and LUAD are the cancer types where DMAC1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DMAC1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	Female	All	−0.223	.002	2	view →
KICH	Female	All	+0.120	.039	2	view →
LUAD	Female	III,IV	−0.152	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

DMAC1P1–ESCA

Open the ESCA breakdown →