DMAC1

Across TCGA patient cohorts, DMAC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,513 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DMAC1-associated proteins across cancer lineages are RANBP6, UHRF2, and PSIP1. Each is linked with DMAC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DMAC1-to-partner and partner-to-DMAC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DMAC1 versus RANBP6 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DMAC1→partner) and Y-score (partner→DMAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RANBP6 →	+0.337	+0.624	<.001	<.001	3	6
LSCC	UHRF2 →	+0.501	+0.652	<.001	<.001	3	6
GBM	PSIP1 →	+0.666	+0.496	<.001	<.001	3	5
LSCC	CDC37L1 →	+0.400	+0.722	<.001	<.001	3	5
LSCC	PLAA →	+0.345	+0.456	<.001	<.001	3	5
CCRCC	TRAM1 →	-0.519	-0.402	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,513 associations by consensus.

DMAC1 vs RANBP6 — BRCA

Explore this scatter interactively →