DMAC1

Across TCGA cell cohorts, DMAC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,406 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DMAC1-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, Positive regulation of neutrophil activation, and NADH dehydrogenase complex assembly. Each is linked with DMAC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both DMAC1-to-partner and partner-to-DMAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by DMAC1-low versus DMAC1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DMAC1→partner) and Y-score (partner→DMAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mitochondrial respiratory chain complex assembly →	+0.067	+0.877	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of neutrophil activation →	+1.624	+1.267	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	NADH dehydrogenase complex assembly →	+0.112	+1.031	<.001	<.001	2	9
UPPER_AERODIGESTIVE_TRACT	Mitochondrial respiratory chain complex I assembly →	+0.112	+1.031	<.001	<.001	2	9
UPPER_AERODIGESTIVE_TRACT	Regulation of blood pressure →	-0.075	-0.864	.001	.001	3	7
BLOOD_Lymphoma	Mitochondrial large ribosomal subunit assembly →	+0.107	+0.939	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,406 associations by consensus.

Mitochondrial respiratory chain complex assembly by DMAC1 expression — BLOOD_Lymphoma

Explore this box plot interactively →