DLX6

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DLX6 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. COAD shows the largest number of these associations.

The most reproducible DLX6-associated genes across cancer lineages are CD4+ Tcm. Each is linked with DLX6 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLX6-to-partner and partner-to-DLX6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by DLX6-low versus DLX6-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLX6→partner) and Y-score (partner→DLX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCD4+ Tcm →+0.023+6.741<.001.01331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tcm by DLX6 expression — COAD

Box plot of CD4+ Tcm in DLX6-low vs DLX6-high samples in COAD.

Explore this box plot interactively →

Exploration