DLX5

Across TCGA patient cohorts, DLX5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,791 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLX5-associated genes across cancer lineages are DUSP16, FZD10, and ADTRP. Each is linked with DLX5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLX5-to-partner and partner-to-DLX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLX5 versus DUSP16 in GBM, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLX5→partner) and Y-score (partner→DLX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DUSP16 →	+0.426	+0.699	.005	<.001	3	2
LSCC	FZD10 →	+1.941	+1.453	<.001	.007	3	2
LSCC	ADTRP →	-1.109	-1.858	.002	<.001	3	2
LSCC	RBM18 →	+0.656	+2.182	.004	.002	3	2
GBM	KANK4 →	+1.716	+0.509	<.001	.003	3	2
LSCC	COG6 →	+0.432	+2.240	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,791 associations by consensus.

DLX5 vs DUSP16 — GBM

Explore this scatter interactively →