DLX5

Across TCGA cell cohorts, DLX5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,966 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DLX5-associated GO terms across cancer lineages are Calcium ion transport, Purine nucleoside triphosphate metabolic process, and mRNA catabolic process. Each is linked with DLX5 in more than 8 cancer types. Because this analysis shows association rather than direction, both DLX5-to-partner and partner-to-DLX5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium ion transport grouped by DLX5-low versus DLX5-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DLX5→partner) and Y-score (partner→DLX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Calcium ion transport →	-0.087	-4.078	<.001	<.001	3	9
OESOPHAGUS	Purine nucleoside triphosphate metabolic process →	+0.071	+2.073	.009	.004	3	9
OESOPHAGUS	mRNA catabolic process →	+0.068	+2.311	.001	.004	3	8
OESOPHAGUS	Nuclear-transcribed mRNA catabolic process →	+0.069	+2.386	<.001	.001	3	8
LUNG_NSCLC_LUSC	Regulation of nucleotide-excision repair →	+0.104	+4.041	<.001	.001	3	8
LUNG_NSCLC_LUSC	Calcium ion transmembrane transport →	-0.055	-3.471	.006	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,966 associations by consensus.

Calcium ion transport by DLX5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →