DLX3

Across TCGA patient cohorts, DLX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,770 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DLX3-associated proteins across cancer lineages are SLC35A1, SEC24A, and SGSM3. Each is linked with DLX3 in more than 4 cancer types. Because this analysis shows association rather than direction, both DLX3-to-partner and partner-to-DLX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLX3 versus SLC35A1 in HNSC, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DLX3→partner) and Y-score (partner→DLX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC35A1 →	-0.600	-1.235	.001	.001	3	5
LSCC	SEC24A →	-0.237	-0.545	<.001	<.001	3	4
PDAC	SGSM3 →	-0.430	-0.234	<.001	.001	3	4
GBM	SIPA1 →	-0.225	-0.085	.006	.009	3	4
UCEC	IQGAP2 →	-0.390	-0.775	.008	.009	3	4
LSCC	MYO1F →	-0.415	-0.787	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,770 associations by consensus.

DLX3 vs SLC35A1 — HNSC

Explore this scatter interactively →