DLX3

Across TCGA cell cohorts, DLX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,741 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible DLX3-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Negative regulation of mRNA metabolic process, and Negative regulation of ubiquitin-dependent protein catabolic process. Each is linked with DLX3 in more than 8 cancer types. Because this analysis shows association rather than direction, both DLX3-to-partner and partner-to-DLX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to nucleus grouped by DLX3-low versus DLX3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DLX3→partner) and Y-score (partner→DLX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protein localization to nucleus →	+0.098	+1.812	<.001	.001	3	9
STOMACH	Negative regulation of mRNA metabolic process →	+0.083	+1.409	<.001	.002	3	8
OESOPHAGUS	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.096	+1.296	<.001	.002	3	8
STOMACH	Negative regulation of RNA catabolic process →	+0.091	+1.987	<.001	.001	3	8
STOMACH	Negative regulation of mRNA catabolic process →	+0.071	+1.447	<.001	.002	3	8
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.144	+2.032	.002	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,741 associations by consensus.

Regulation of protein localization to nucleus by DLX3 expression — STOMACH

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