DLX2

Across TCGA patient cohorts, DLX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,232 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DLX2-associated proteins across cancer lineages are KCNQ1_S27, ARHGAP30_S709, and MDM1_S601. Each is linked with DLX2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DLX2-to-partner and partner-to-DLX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLX2 versus KCNQ1_S27 in LSCC, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DLX2→partner) and Y-score (partner→DLX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KCNQ1_S27 →	-0.667	-0.452	<.001	.003	3	3
LSCC	ARHGAP30_S709 →	-0.572	-0.601	<.001	<.001	3	3
LSCC	MDM1_S601 →	-0.490	-0.871	<.001	.005	3	3
LSCC	MYO1F_S1023 →	-0.609	-0.445	<.001	.004	3	3
BRCA	CARD9 →	-0.390	-1.338	<.001	<.001	3	3
LSCC	PHF14 →	+0.164	+0.432	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,232 associations by consensus.

DLX2 vs KCNQ1_S27 — LSCC

Explore this scatter interactively →