DLX2

Across TCGA patient cohorts, DLX2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,208 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DLX2-associated genes across cancer lineages are DNM1, RBSN, and ZFP1. Each is linked with DLX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLX2-to-partner and partner-to-DLX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLX2 versus DNM1 in GBM, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLX2→partner) and Y-score (partner→DLX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DNM1 →	-1.014	-0.699	.005	.007	3	2
PDAC	RBSN →	-0.266	-0.527	.004	.002	3	2
GBM	ZFP1 →	-0.464	-0.617	.003	.002	3	2
PDAC	RN7SL269P →	-0.957	-0.942	.002	<.001	3	2
PDAC	MIR4755 →	-1.368	-0.839	.001	.001	3	2
PDAC	PHLPP2 →	-0.482	-0.679	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,208 associations by consensus.

DLX2 vs DNM1 — GBM

Explore this scatter interactively →