DLX1

Across TCGA cell cohorts, DLX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,891 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible DLX1-associated GO terms across cancer lineages are Regulation of amacrine cell differentiation, Heterochromatin formation, and Centrosome cycle. Each is linked with DLX1 in more than 19 cancer types. Because this analysis shows association rather than direction, both DLX1-to-partner and partner-to-DLX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of amacrine cell differentiation grouped by DLX1-low versus DLX1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DLX1→partner) and Y-score (partner→DLX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of amacrine cell differentiation →	+1.511	+2.864	<.001	<.001	3	20
STOMACH	Heterochromatin formation →	+0.088	+2.719	<.001	<.001	3	13
SOFT_TISSUE	Centrosome cycle →	+0.055	+1.549	<.001	<.001	3	13
STOMACH	Nuclear transport →	+0.075	+2.673	.005	<.001	3	12
SOFT_TISSUE	Regulation of chromosome segregation →	+0.102	+1.812	<.001	<.001	3	12
STOMACH	Nucleocytoplasmic transport →	+0.075	+2.673	.005	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,891 associations by consensus.

Regulation of amacrine cell differentiation by DLX1 expression — LUNG_SCLC

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