DLST

Across TCGA cell cohorts, DLST RNA expression is significantly associated with the RNA expression of many other genes, with 9,958 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DLST-associated genes across cancer lineages are AREL1, COQ6, and SNW1. Each is linked with DLST in more than 19 cancer types. Because this analysis shows association rather than direction, both DLST-to-partner and partner-to-DLST results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLST versus AREL1 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.81.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLST→partner) and Y-score (partner→DLST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	AREL1 →	+1.040	+0.900	<.001	<.001	3	20
URINARY_TRACT	COQ6 →	+1.237	+1.054	<.001	<.001	3	19
SOFT_TISSUE	SNW1 →	+0.849	+0.831	<.001	<.001	3	19
PANCREAS	GPATCH2L →	+1.169	+0.793	<.001	<.001	3	18
KIDNEY	YLPM1 →	+1.050	+0.749	<.001	<.001	3	18
OESOPHAGUS	TTLL5 →	+1.033	+0.602	<.001	.004	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,958 associations by consensus.

DLST vs AREL1 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →