Across TCGA patient cohorts, DLK1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLK1-associated genes across cancer lineages are Cyclin-B1, PCNA, and FoxM1. Each is linked with DLK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DLK1-to-partner and partner-to-DLK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLK1→partner) and Y-score (partner→DLK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.458	+2.459	.033	.019	3	3
UCEC	PCNA →	+0.189	+3.169	.022	.018	3	2
LUAD	FoxM1 →	+0.591	+2.820	<.001	.035	3	1
LUAD	4E-BP1_pT70 →	+0.290	+2.824	.008	.036	2	2
UCEC	MEK1 →	+0.307	+1.700	.028	.042	3	1
UCEC	p62 Lck ligand →	+0.253	+1.678	.042	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

DLK1 survival (RNA) · tumor vs normal (RNA) · all DLK1 data types