Across TCGA cell cohorts, DLK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,513 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DLK1-associated GO terms across cancer lineages are Negative regulation of canonical Wnt signaling pathway, Response to rapamycin, and Negative regulation of adaptive immune response. Each is linked with DLK1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DLK1-to-partner and partner-to-DLK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DLK1→partner) and Y-score (partner→DLK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of canonical Wnt signaling pathway →	+0.050	+0.044	<.001	.002	3	4
LUNG_SCLC	Response to rapamycin →	+0.106	+3.906	<.001	<.001	3	4
LUNG_SCLC	Negative regulation of adaptive immune response →	-0.069	-4.633	<.001	<.001	3	4
URINARY_TRACT	Negative regulation of PERK-mediated unfolded protein response →	+0.115	+0.062	.003	.004	3	4
URINARY_TRACT	Response to methionine →	+0.069	+0.056	<.001	<.001	3	4
BLOOD_Leukemia	L-methionine biosynthetic process →	+0.114	+1.984	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,513 associations by consensus.

Exploration

DLK1 survival (RNA) · tumor vs normal (RNA) · all DLK1 data types