DLGAP5

Across TCGA cell cohorts, DLGAP5 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DLGAP5-associated genes across cancer lineages are GHRHR, ADGB, and FOXE3. Each is linked with DLGAP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLGAP5-to-partner and partner-to-DLGAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by DLGAP5-low versus DLGAP5-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP5→partner) and Y-score (partner→DLGAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GHRHR →	+0.069	+5.087	<.001	.004	3	1
LARGE_INTESTINE	ADGB →	+0.359	+2.554	<.001	.006	3	1
LARGE_INTESTINE	FOXE3 →	+0.098	+3.389	.005	.007	3	1
LARGE_INTESTINE	SPINK9 →	+0.190	+2.793	.002	.002	3	1
LUNG_NSCLC_LUAD	LIM2 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	C1QC →	+0.019	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

GHRHR by DLGAP5 expression — URINARY_TRACT

Explore this box plot interactively →