DLGAP3

Across TCGA patient cohorts, DLGAP3 mutation is significantly associated with the RNA expression of many other genes, with 1,801 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLGAP3-associated genes across cancer lineages are CDCA2, GUF1, and MON1A. Each is linked with DLGAP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both DLGAP3-to-partner and partner-to-DLGAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCA2 grouped by DLGAP3-low versus DLGAP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP3→partner) and Y-score (partner→DLGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA2 →	+0.817	+2.392	<.001	<.001	3	4
UCEC	GUF1 →	+0.455	+2.157	<.001	.009	3	3
UCEC	MON1A →	+0.303	+2.233	.003	.005	3	3
UCEC	SFXN1 →	+0.411	+2.980	.002	<.001	3	3
UCEC	ZNF367 →	+0.610	+2.254	.002	.005	3	3
UCEC	ZMYND19 →	+0.329	+2.032	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,801 associations by consensus.

CDCA2 by DLGAP3 expression — UCEC

Explore this box plot interactively →