DLGAP1

Across TCGA patient cohorts, DLGAP1 mutation is significantly associated with the RNA expression of many other genes, with 4,859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLGAP1-associated genes across cancer lineages are RPL4P6, B3GNT4, and ADNP2. Each is linked with DLGAP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DLGAP1-to-partner and partner-to-DLGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL4P6 grouped by DLGAP1-low versus DLGAP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP1→partner) and Y-score (partner→DLGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL4P6 →	+0.211	+1.884	.006	<.001	3	5
LUSC	B3GNT4 →	+0.583	+3.217	.002	.009	3	4
UCEC	ADNP2 →	+0.531	+2.280	<.001	<.001	3	4
UCEC	XPNPEP1 →	+0.407	+1.628	<.001	<.001	3	4
UCEC	RNU2-27P →	+0.465	+1.823	.007	.002	3	4
UCEC	ATP2A1-AS1 →	+0.755	+1.660	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,859 associations by consensus.

RPL4P6 by DLGAP1 expression — UCEC

Explore this box plot interactively →