DLGAP1-AS5

Across TCGA pan-cancer cohorts, DLGAP1-AS5 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of DLGAP1-AS5’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where DLGAP1-AS5 RNA is repressed in tumor relative to normal tissue. In most cancer types DLGAP1-AS5 is over-expressed in tumor, although a few such as HNSC and UCEC show the opposite, repressed pattern.

HNSC, UCEC, and COAD are the cancer types where DLGAP1-AS5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DLGAP1-AS5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	−1.263	<.001	11	view →
UCEC	All	II,III,IV	−0.195	<.001	6	view →
COAD	All	II,III,IV	+0.297	.007	4	view →
KIRP	Female	All	−0.042	.033	3	view →
BRCA	Female	II,III,IV	−0.264	.015	2	view →
LUAD	All	All	+0.181	.029	1	view →
CHOL	All	All	+0.046	.038	1	view →
KIRC	Female	IV	−0.041	.017	1	view →
THCA	All	All	−0.004	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

DLGAP1-AS5–HNSC

Open the HNSC breakdown →