DLG3

Across TCGA patient cohorts, DLG3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,760 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DLG3-associated proteins across cancer lineages are PLEKHO2, WAS, and ARFGEF3. Each is linked with DLG3 in more than 6 cancer types. Because this analysis shows association rather than direction, both DLG3-to-partner and partner-to-DLG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLG3 versus PLEKHO2 in GBM, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DLG3→partner) and Y-score (partner→DLG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEKHO2 →	-0.434	-0.512	<.001	<.001	3	7
LSCC	WAS →	-0.484	-0.793	<.001	<.001	3	6
HNSC	ARFGEF3 →	+0.583	+0.516	<.001	.002	3	6
LSCC	PEX1 →	+0.312	+0.524	<.001	.001	3	6
GBM	PLCG2 →	-0.673	-0.626	<.001	<.001	3	6
LUAD	THEMIS2 →	-0.372	-0.590	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,760 associations by consensus.

DLG3 vs PLEKHO2 — GBM

Explore this scatter interactively →