DLG3

Across TCGA cell cohorts, DLG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,629 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DLG3-associated GO terms across cancer lineages are Copper ion export, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Establishment of epithelial cell apical/basal polarity. Each is linked with DLG3 in more than 11 cancer types. Because this analysis shows association rather than direction, both DLG3-to-partner and partner-to-DLG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by DLG3-low versus DLG3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DLG3→partner) and Y-score (partner→DLG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Copper ion export →	-0.158	-1.624	<.001	<.001	3	12
LUNG_SCLC	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.185	+1.912	<.001	.001	3	10
STOMACH	Establishment of epithelial cell apical/basal polarity →	-0.201	-1.929	<.001	<.001	3	10
LUNG_SCLC	Regulation of organelle assembly →	+0.044	+1.562	<.001	.001	2	11
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.089	+0.992	<.001	.009	3	10
STOMACH	Regulation of plasma lipoprotein particle levels →	-0.126	-1.790	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,629 associations by consensus.

Copper ion export by DLG3 expression — BONE

Explore this box plot interactively →