DLG2

Across TCGA patient cohorts, DLG2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,864 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DLG2-associated genes across cancer lineages are TNFSF12, HTR2A, and PDE1A. Each is linked with DLG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DLG2-to-partner and partner-to-DLG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLG2 versus TNFSF12 in BRCA, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLG2→partner) and Y-score (partner→DLG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TNFSF12 →	+1.072	+0.738	.004	.003	3	4
GBM	HTR2A →	+1.229	+0.684	<.001	<.001	3	4
GBM	PDE1A →	+0.771	+0.588	<.001	<.001	3	4
GBM	CNRIP1 →	+0.659	+0.455	.001	.002	3	4
GBM	LDHAL6DP →	+0.861	+0.625	<.001	<.001	3	4
GBM	NAV3 →	+1.226	+0.652	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,864 associations by consensus.

DLG2 vs TNFSF12 — BRCA

Explore this scatter interactively →