DLG1

Across TCGA pan-cancer cohorts, DLG1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DLG1 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DLG1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DLG1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and COAD are the cancer types where DLG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	II,III,IV	0.970	0.745	.014	15	view →
UCEC	DFS	Tertile	All	1.000	0.838	.002	12	view →
COAD	DFS	Tertile	II,III,IV	1.000	0.911	.037	12	view →
LUAD	OS	Tertile	II,III,IV	0.871	0.320	.012	4	view →
HNSC	DFS	Median	II,III,IV	0.975	0.898	.036	3	view →
CCRCC	OS	Median	All	1.000	0.764	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DLG1–PDAC (OS)

Open the PDAC breakdown →