DLG1

Across TCGA patient cohorts, DLG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,334 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DLG1-associated proteins across cancer lineages are PAK2, NMD3, and OPA1. Each is linked with DLG1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DLG1-to-partner and partner-to-DLG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLG1 versus PAK2 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DLG1→partner) and Y-score (partner→DLG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PAK2 →	+0.266	+0.753	<.001	<.001	3	7
OV	NMD3 →	+0.262	+0.595	.002	.004	3	6
LSCC	OPA1 →	+0.457	+0.846	<.001	<.001	3	6
LSCC	PCYT1A →	+0.609	+0.682	<.001	<.001	3	6
HNSC	FXR1 →	+0.478	+0.728	<.001	<.001	3	6
HNSC	TBL1XR1 →	+0.473	+0.880	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,334 associations by consensus.

DLG1 vs PAK2 — LSCC

Explore this scatter interactively →