Across TCGA patient cohorts, DLEU7 mutation is significantly associated with the RNA expression of many other genes, with 242 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLEU7-associated genes across cancer lineages are PACERR, TAF9, and MIR4727. Each is linked with DLEU7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLEU7-to-partner and partner-to-DLEU7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLEU7→partner) and Y-score (partner→DLEU7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PACERR →	+0.413	+3.700	.008	.001	3	1
UCEC	TAF9 →	+0.603	+3.459	.001	.005	3	1
UCEC	MIR4727 →	+0.405	+3.229	<.001	.001	3	1
UCEC	UHRF1 →	+0.794	+3.711	.008	<.001	3	1
UCEC	PIGW →	+0.591	+3.711	.009	<.001	3	1
UCEC	CCDC134 →	+0.584	+3.721	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 242 associations by consensus.

Exploration

DLEU7 survival (RNA) · tumor vs normal (RNA) · all DLEU7 data types