Across TCGA patient cohorts, DLEU7 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DLEU7-associated genes across cancer lineages are Fibroblasts, Endothelial cells, and lymphatic Endothelial cells. Each is linked with DLEU7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLEU7-to-partner and partner-to-DLEU7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLEU7→partner) and Y-score (partner→DLEU7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Fibroblasts →	+0.025	+5.721	.044	.036	3	1
UCEC	Endothelial cells →	-0.039	-3.148	.028	.019	3	1
UCEC	lymphatic Endothelial cells →	-0.022	-3.281	.048	.010	3	1
UCEC	mv Endothelial cells →	-0.026	-3.000	.017	.036	3	1
UCEC	Myocytes →	+0.036	+3.743	.016	<.001	3	1
UCEC	NKT →	-0.108	-3.145	.030	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

DLEU7 survival (RNA) · tumor vs normal (RNA) · all DLEU7 data types