Across TCGA cell cohorts, DLEU7 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DLEU7-associated genes across cancer lineages are IFNG, TPD52L3, and KRTAP17-1. Each is linked with DLEU7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLEU7-to-partner and partner-to-DLEU7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLEU7→partner) and Y-score (partner→DLEU7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IFNG →	+0.225	+4.152	<.001	.009	3	1
BLOOD_Leukemia	TPD52L3 →	+0.014	+4.539	<.001	.007	3	1
BLOOD_Leukemia	KRTAP17-1 →	+0.680	+5.060	.008	.001	3	1
BLOOD_Leukemia	TMEM244 →	+0.354	+4.551	<.001	.004	3	1
BLOOD_Leukemia	OR5H6 →	+0.427	+4.705	<.001	.003	3	1
BLOOD_Leukemia	OR10A6 →	+0.053	+5.786	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

DLEU7 survival (RNA) · tumor vs normal (RNA) · all DLEU7 data types