DLEU1

Across TCGA cell cohorts, DLEU1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DLEU1-associated genes across cancer lineages are RNASE8, C9orf92, and CT45A7. Each is linked with DLEU1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLEU1-to-partner and partner-to-DLEU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASE8 grouped by DLEU1-low versus DLEU1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLEU1→partner) and Y-score (partner→DLEU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RNASE8 →	+0.029	+5.369	<.001	.004	3	1
SOFT_TISSUE	C9orf92 →	+0.194	+5.369	<.001	.004	3	1
SOFT_TISSUE	CT45A7 →	+0.031	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

RNASE8 by DLEU1 expression — SOFT_TISSUE

Explore this box plot interactively →